Spontaneous Heparin-Induced Thrombocytopenia Presenting as Concomitant Bilateral Cerebrovascular Infarction and Acute Coronary Syndrome

Background: Spontaneous heparin-induced thrombocytopenia is a pro-thrombotic syndrome in which anti-heparin antibodies develop without heparin exposure. Case presentation: A 78-year-old man who underwent successful lumbar laminectomy presented to the hospital 5 days after discharge for stroke-like symptoms and was found have acute infarcts of bilateral frontal lobes. The patient be severely thrombocytopenic incidentally an inferior wall myocardial infarction. Further investigation led diagnosis lower extremity deep vein thromboses. His overall clinical presentation prompted detailed hematologic workup that indicated positivity despite no previous exposure products. Conclusions: This case illustrates with prior lifetime subsequent development lobes, infarction, thromboses, concern sequelae spontaneous thrombocytopenia.